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NeuroSAFE PROOF Randomised Controlled Feasibility Study: Brief Report of Perioperative Outcomes, Histological Concordance, and Feasibility

Erectile dysfunction is a common and significant side effect of radical prostatectomy (RP). Nerve-sparing (NS) RP improves recovery of erectile function, but the quality of NS can be impaired by concern about the oncological risks of positive surgical margins (PSM). The NeuroSAFE technique is an approach…

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NeuroSAFE frozen section during robot‐assisted radical prostatectomy (RARP): Peri‐operative and Histopathological Outcomes from the NeuroSAFE PROOF Feasibility Randomised Controlled Trial

This feasibility study demonstrates the safety, the reproducibility and the excellent histopathological concordance of the NeuroSAFE technique in the NeuroSAFE PROOF trial. Though the technique increases the duration of RARP, this does not cause short‐term harm. Confirmation of feasibility has led to the opening of the fully powered NeuroSAFE PROOF RCT, which is currently underway at 4 sites in the UK.

NCRI Virtual Showcase

Each year the National Cancer Research Institute hosts the UK’s largest cancer conference to bring together the brightest scientific and medical minds to advance cancer research in the UK. Due to the COVID-19 pandemic, 2020’s conference was postponed and in it’s place was the NCRI Virtual Showcase which took place Monday 2 – Tuesday 3 November 2020.

The NeuroSAFE PROOF Study featured in the session ‘Living with and beyond cancer: Sexuality and sexual health’ and was presented by our Associate Principal Investigator Mr Eoin Dinneen